High-Performance Bioprocessing Products
At enGenes, we create high-performance tools to transform bioprocessing — from upstream fermentation to downstream purification.
Our product portfolio includes a cost-effective endonuclease and a versatile range of affinity ligands, all produced with our proprietary -eXpress, -eXtra, and -eXcite platforms to deliver reliability, scalability, and efficiency.


eXrase
eXrase™ – Smart DNA Digestion, Real Cost Savings
eXrase is a next-generation recombinant endonuclease that delivers powerful DNA/RNA digestion at a fraction of the cost of traditional market enzymes — without compromising performance.
Key Benefits:
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Up to 30× cost savings vs Benzonase® and similar nucleases
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Rapid reduction of lysate viscosity, enabling smoother downstream handling
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Improved chromatographic flow rates and higher protein yields
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Manufactured with -eXpress and -eXtra for consistent, scalable production
Applications:
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Viscosity control during cell harvest and clarification
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Enhanced filtration and purification throughput
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Increased recovery and purity of target proteins
Available in research-grade, technical-grade, and bulk formats.


Affinity Ligands
Affinity Ligands – High-Performance Capture, Without the High Cost
Our affinity ligands are designed to support efficient and selective purification of biotherapeutics, from discovery to large-scale manufacturing — without the price tag of traditional solutions.
Product Portfolio:
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Wild-Type Protein A
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Protein A with C-terminal Cysteine (for site-specific, directional immobilization)
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Synthetic Tetrameric and Hexameric Ligands
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Custom Ligands tailored to specific targets or processes
Manufactured using -eXpress and -eXtra, with optional -eXcite for full end-to-end continuous production.
Why It Matters:
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Optimized for high-efficiency capture of antibodies and proteins
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Offers exceptional binding stability and low leaching risk
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Enables site-specific, directional immobilization for enhanced process control
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Supports cost-effective custom resin development using alternative Protein A sources — unlocking more affordable, tailored bioprocessing solutions